Li-Wei Chen Selected Research

19- nor- 2- (3- hydroxypropyl)- 1,25- dihydroxyvitamin D3

7/2018	MART-10, a 1α,25(OH)2D3 Analog, Potently Represses Metastasis of ER+ Breast Cancer Cells with VEGF-A Overexpression.
11/2017	1α,25(OH)2D3 Analog, MART-10, Inhibits Neuroendocrine Tumor Cell Metastasis After VEGF-A Stimulation.
7/2016	1α,25(OH)2D3 Analog, MART-10, Inhibits Neuroendocrine Tumor Cell Growth Through Induction of G0/G1 Cell-cycle Arrest and Apoptosis.
4/2016	The Vitamin D Analog, MART-10, Attenuates Triple Negative Breast Cancer Cells Metastatic Potential.
1/2016	MART-10, the new brand of 1α,25(OH)2D3 analog, is a potent anti-angiogenic agent in vivo and in vitro.
12/2015	MART-10, the vitamin D analog, is a potent drug to inhibit anaplastic thyroid cancer cell metastatic potential.
11/2014	The vitamin D analog, MART-10, represses metastasis potential via downregulation of epithelial-mesenchymal transition in pancreatic cancer cells.
1/2014	MART-10, a less calcemic vitamin D analog, is more potent than 1α,25-dihydroxyvitamin D3 in inhibiting the metastatic potential of MCF-7 breast cancer cells in vitro.
11/2013	MART-10, a novel vitamin D analog, inhibits head and neck squamous carcinoma cells growth through cell cycle arrest at G0/G1 with upregulation of p21 and p27 and downregulation of telomerase.

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Li-Wei Chen Research Topics

Disease

14	Neoplasms (Cancer) 11/2023 - 11/2013
10	Neoplasm Metastasis (Metastasis) 01/2019 - 07/2012
7	Fibrosis (Cirrhosis) 12/2023 - 03/2015
7	Infections 01/2022 - 12/2007
6	Hepatocellular Carcinoma (Hepatoma) 01/2023 - 11/2015
5	Breast Neoplasms (Breast Cancer) 07/2018 - 01/2014
5	Hypercalcemia (Milk Alkali Syndrome) 01/2016 - 11/2013
4	Chronic Hepatitis C 01/2018 - 02/2010
3	Non-alcoholic Fatty Liver Disease 04/2023 - 07/2019
3	Fatty Liver 12/2022 - 01/2020
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 09/2021 - 05/2016
2	Adenocarcinoma of Lung 11/2023 - 01/2022
2	Ascites 01/2023 - 10/2022
2	Hepatitis B 01/2023 - 01/2017
2	Chronic Renal Insufficiency 09/2021 - 01/2017
2	Vitamin D Deficiency 07/2019 - 05/2016
2	Cholangiocarcinoma 01/2019 - 08/2016
2	Neuroendocrine Tumors (Neuroendocrine Tumor) 11/2017 - 07/2016
1	Body Weight (Weight, Body) 12/2023
1	Inflammation (Inflammations) 12/2023
1	Hyperemia 06/2023
1	Abdominal Obesity 02/2023
1	Gallstones (Gallstone) 02/2023
1	Thrombosis (Thrombus) 01/2023
1	Gestational Diabetes (Gestational Diabetes Mellitus) 01/2023
1	Liver Cirrhosis (Hepatic Cirrhosis) 12/2022
1	Hyperferritinemia 12/2022
1	Chronic Hepatitis B 01/2022
1	Chronic Hepatitis (Chronic Active Hepatitis) 01/2022
1	Diabetes Mellitus 09/2021
1	Adenocarcinoma 01/2021
1	Gastritis 01/2021
1	Metaplasia 01/2021
1	Acne Vulgaris 09/2020
1	Lung Neoplasms (Lung Cancer) 03/2019
1	Bone Fractures (Bone Fracture) 01/2017
1	Albuminuria 01/2017
1	Hypertriglyceridemia 01/2017
1	Insulin Resistance 01/2017
1	Triple Negative Breast Neoplasms 04/2016
1	Abdominal Pain (Pain, Abdominal) 04/2016

Drug/Important Bio-Agent (IBA)

11	hydroxide ionIBA 07/2018 - 11/2013
10	Vitamin D FDA LinkGeneric 07/2019 - 11/2013
9	19- nor- 2- (3- hydroxypropyl)- 1,25- dihydroxyvitamin D3IBA 07/2018 - 11/2013
4	AdiponectinIBA 09/2021 - 05/2016
4	InterferonsIBA 01/2019 - 02/2010
4	Ribavirin (Virazole)FDA LinkGeneric 01/2018 - 02/2010
3	Alanine Transaminase (SGPT)IBA 04/2023 - 01/2019
3	C-Reactive ProteinIBA 09/2021 - 05/2016
3	LeptinIBA 07/2019 - 05/2016
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2019 - 11/2017
2	VimentinIBA 12/2023 - 11/2014
2	xylometazoline (stas)IBA 11/2023 - 01/2022
2	Aldehyde DehydrogenaseIBA 04/2023 - 01/2019
2	Sorafenib (BAY 43-9006)FDA Link 01/2023 - 01/2023
2	Antiviral Agents (Antivirals)IBA 01/2022 - 11/2016
2	gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA 09/2021 - 01/2020
2	Calcitriol Receptors (Calcitriol Receptor)IBA 01/2021 - 07/2016
2	CytokinesIBA 07/2019 - 01/2017
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2019 - 01/2015
2	AdipokinesIBA 07/2019 - 01/2017
2	Hepatitis B Surface Antigens (HBsAg)FDA Link 01/2019 - 01/2017
2	25-Hydroxyvitamin D3 1-alpha-Hydroxylase (25 Hydroxyvitamin D3 1 alpha Hydroxylase)IBA 08/2016 - 11/2015
2	Phosphoric Monoester Hydrolases (Phosphatases)IBA 08/2016 - 01/2015
2	TensinsIBA 08/2016 - 01/2015
1	CollagenIBA 12/2023
1	Fibronectins (Fibronectin)IBA 12/2023
1	Alcohol Dehydrogenase (Alcohol Dehydrogenase (NAD+))IBA 04/2023
1	EnzymesIBA 04/2023
1	baysilon (polydimethylsiloxane)IBA 03/2023
1	Hormones (Hormone)IBA 02/2023
1	Tyrosine Kinase InhibitorsIBA 01/2023
1	hepatitis B virus X proteinIBA 01/2023
1	lenvatinibIBA 01/2023
1	Folic Acid (Vitamin M)FDA LinkGeneric 01/2023
1	Uric Acid (Urate)IBA 12/2022
1	Ferritins (Ferritin)IBA 12/2022
1	Tenofovir (Viread)FDA Link 01/2022
1	entecavir FDA Link 01/2022
1	CholesterolIBA 09/2021
1	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 09/2021
1	DiterpenesIBA 09/2020
1	Triglycerides (Triacylglycerol)IBA 01/2020
1	Erythropoietin FDA Link 01/2019
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2019
1	Conditioned Culture MediaIBA 01/2019
1	Proteins (Proteins, Gene)FDA Link 01/2019
1	Estrogen ReceptorsIBA 07/2018
1	Parathyroid Hormone (Parathormone)IBA 01/2017
1	Phosphates (Orthophosphate)IBA 01/2017
1	CalciumIBA 01/2017
1	Biomarkers (Surrogate Marker)IBA 01/2017
1	Urea (Carbamide)FDA LinkGeneric 05/2016
1	Pain-FreeIBA 04/2016
1	MineralsIBA 01/2016

Therapy/Procedure

8	Therapeutics 01/2023 - 12/2007
2	Radiotherapy 11/2013 - 07/2012
1	Free Tissue Flaps 06/2023
1	Radiofrequency Ablation 10/2022
1	Segmental Mastectomy (Lumpectomy) 03/2019